Because they are reported voluntarily from a population of unknown size, estimates and frequency cannot be made. This medication should be used only when clearly needed during pregnancy. 23/5, 5th Cross, GKM College Road Jaraganahalli, JP Nagar, Jaraganahalli, Bengaluru - 560078, Dist. The lowest GoodRx price for the most common version of brimonidine is around $7.80, 73% off the average retail price of $29.64. OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. A great relief after Caremark denied my meds in January! INACTIVES:   Citric Acid, Polyvinyl Alcohol, Sodium Chloride, Sodium Citrate, Purified Water. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication. Place one finger at the corner of your eye (near the nose) and apply gentle pressure. Repeat these steps for your other eye if so directed by your doctor. Brand Names: Alphagan P. This medication is used to treat open-angle glaucoma or high fluid pressure in the eye. It is important to continue this medication even if you do not have any symptoms. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. To avoid contamination, do not touch the dropper tip or let it touch your eye or any other surface. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. wellness products. Remember to use it at the same times each day. In humans, systemic metabolism of brimonidine is extensive. | BRIMONIDINE (bri MOE ni deen) is used to to treat open-angle glaucoma and high pressure in the eye.. Price Drugs My Savings Card Brand names for brimonidine ophthalmic include Alphagan P. Brimonidine ophthalmic Prices. !”, “Always pleased with my order and prompt shipping. Reproductive studies performed in rats with oral doses of 0.66 mg base/kg revealed no evidence of harm to the fetus due to brimonidine tartrate ophthalmic solution 0.2%. A high fluid pressure in the eye can cause nerve damage, vision loss or even blindness. It is not known whether the concurrent use of these agents with brimonidine tartrate ophthalmic solution 0.2% in humans can lead to resulting interference with the IOP lowering effect. PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to apraclonidine; or if you have any other allergies. … Use eye drops before eye ointments to allow the eye drops to enter the eye. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Popular categories include: “Just received first order and shipping was fast. Brimonidine/timolol (Combigan) is an expensive drug used in the eye to treat open-angle glaucoma and high pressure in the eyes. Are you sure you only want to order ? As a VIPPS accredited pharmacy licensed and/or authorized in all 50 states, pharmacy regulation requires us to ask for your shipping zip code. There are no adequate and well-controlled studies in pregnant women. The e-mail follow-up is also important to let one know that the order has been shipped. In solution, brimonidine tartrate ophthalmic solution 0.2% has a clear, greenish-yellow color. Replace the dropper cap after each use. The Lumify brand of brimonidine ophthalmic is available without a prescription, and is used to relieve eye … This drug should not be used with the following medications because very serious interactions may occur: MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine). A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Brimonidine tartrate was not mutagenic or cytogenic in a series of in vitro and in vivo studies including the Ames test, chromosomal aberation assay in Chinese Hamster Ovary (CHO) cells, a host-mediated assay and cytogenic studies in mice, and dominant lethal assay. (Also refer to Adverse Reactions section). Events occurring in approximately 3-9% of the subjects, in descending order included cor-neal staining/erosion, photophobia, eyelid erythemia, ocular ache/pain, ocular dryness, tearing, upper respiratory symptoms, eyelid edema, conjunctival edema, dizziness, blepharitis, ocular irritation, gastrointestinal symptoms, asthenia, conjunctival blanching, abnormal vision and muscular pain. Ask the doctor or pharmacist for details. Caution in using concomitant drugs such as beta-blockers (ophthalmic and systemic), antihypertensives and/or cardiac glycosides is advised. Do not double the dose to catch up. A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. ACTIVE:   Brimonidine tartrate: 0.2% (2 mg/mL). Look downward and gently close your eyes for 1 to 2 minutes. This medicine is an alpha … The lowest GoodRx price for the most common version of brimonidine is around $7.80, 73% off the average retail price of $29.53. This drug may make you dizzy or drowsy or cause blurred vision. Try not to blink and do not rub your eye. Brimonidine tartrate ophthalmic solution 0.2% is indicated for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. 1. Chemical Name:   5-bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate. There are currently no generic alternatives for Combigan. Consult your doctor before breast-feeding. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Pediatric Use:   In a well-controlled clinical study conducted in pediatric glaucoma patients (ages 2 to 7 years) the most commonly observed adverse events with brimonidine tartrate ophthalmic solution 0.2% dosed three times daily were somnolence (50% - 83% in patients ages 2 to 6 years) and decreased alertness. Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye. If you contact our Customer Support by one of the methods below, we will be able to assist you in locating the product you are looking for. Discuss the risks and benefits with your doctor. You'll never have to wait around at the pharmacy again - we deliver your medications right to your door. DRUG INTERACTIONS: Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: beta-blockers (e.g., atenolol, metoprolol, timolol eye drops), digoxin, high blood pressure medications (e.g., clonidine, terazosin), tricyclic antidepressants (e.g., amitriptyline). If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying the other medications. The concentration of brimonidine in the blood peaked 1 to 4 hours after the eye drops were administered. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Brimonidine tartrate ophthalmic solution 0.2%, We comply with the HONcode standard for trustworthy health information -. The events, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to brimonidine tartrate ophthalmic solution 0.2%, or a combination of these factors, include: bradycardia; hypotension; iritis; miosis; skin reactions (including erythema, eyelid pruritus, rash, and vasodilation); and tachycardia. Composition: Brimonidine Tartrate Ophthalmic. Rs 15/ Piece Get Latest Price. Tell your doctor immediately if any of these rare but very serious side effects occur: fainting, slow/irregular heartbeats. Approximately 87% of an orally-administered radioactive dose was eliminated within 120 hours, with 74% found in the urine. This drug is not recommended for use in children less than 2 years of age due to an increased risk of serious side effects such as very slowed breathing. 3. In Canada - Call your doctor for medical advice about side effects. Apnea, bradycardia, hypotension, hypothermia, hypotonia, and somnolence have been reported in infants receiving brimonidine tartrate ophthalmic solution 0.2%. DO NOT USE IF IMPRINTED "Protective Seal" WITH YELLOW IS NOT INTACT. BRIMONIDINE is used to to treat open-angle glaucoma and high pressure in the eye. https://www.cvs.com/drug/brimonidine/ophthalmic-drops-solution/0_15pc Brimonidine Tartrate Ophthalmic Solution 0.2% is a relatively selective alpha-2 adrenergic agonist for ophthalmic use. The most commonly observed adverse event was somnolence. … If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying the other medications. Repeat these steps for your other eye if so directed by your doctor. You may report side effects to Health Canada at 1-866-234-2345. The Alphagan P brand of brimonidine ophthalmic is available only with a prescription. Properly discard this product when it is expired or no longer needed. No information is available on overdosage in humans. Use this medication regularly in order to get the most benefit from it. Brimonidine tartrate ophthalmic solution 0.2% may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. If you are using another kind of eye medication (e.g., drops or ointments), wait at least 5 minutes before applying the other medications. Thanks! Do not rinse the dropper. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. The safety and effectiveness of brimonidine tartrate ophthalmic solution 0.2% have not been studied in pediatric patients below the age of 2 years. Based in Florence, Kentucky, Healthwarehouse.com is the leader in Digital Pharmacy and a pioneer in affordable healthcare, providing incredible patient services since 2007. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Brimonidine tartrate has the action of lowering intraocular pressure with minimal effect on cardiovascular and pulmonary parameters. Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye. It has an osmolality of 280-330 mOsml/kg and a pH of 5.6-6.6 The structural formula isChemical Name: 5-bromo-6-(2-imidazolidinylideneamino) quinoxaline L-tartrate.CAS Number 59803-98-4Each mL Contains:ACTIVE: Brimonidine t… PRESERVATIVE ADDED:   Benzalkonium Chloride (0.05 mg). Mechanism of Action:   Brimonidine tartrate ophthalmic solution 0.2% is an alpha adrenergic receptor agonist. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Squeeze the upturned dropper bottle to release a drop into your eye… Information last revised October 2011. The following events have been identified during post-marketing use of brimonidine tartrate ophthalmic solution 0.2% in clinical practice. This medication lowers pressure by allowing better fluid drainage from within the eye and also by reducing the amount of fluid formed in the eye. Apply your eye drops in the following way: 3 1. Brimonidine tartrate ophthalmic solution 0.2% should be used during pregnancy only if the potential benefit to the mother justifies the potential risk to the fetus. Pregnancy:   Teratogenic Effects:  Pregnancy Category B. No data on the level of circulating catecholamines after brimonidine tartrate ophthalmic solution 0.2% are available. Tilt your head back, look upward and pull down the lower eyelid to make a pouch. WARNING: You`ve selected a custom quantity of . Brimonidine tartrate ophthalmic solution 0.2% is not recommended for use in pediatric patients under the age of 2 years. Azopt Eye Drops Ask Price Sumukha Pharma Jaraganahalli, Bengaluru No. … Alphagan P (brimonidine ophthalmic) is a member of the ophthalmic glaucoma agents drug class and is commonly used for Glaucoma - Open Angle and Intraocular Hypertension. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss. Caution, however, is advised in patients taking tricyclic antidepressants which can affect the metabolism and uptake of circulating amines. Browse our extensive selection of health and Brimodin Eye Drop. In these studies, dietary administration of brimonidine tartrate at doses up to 2.5 mg/kg/day in mice and 1.0 mg/kg/day in rats achieved ~77 and 118 times, respectively, the plasma drug concentration estimated in humans treated with one drop brimonidine tartrate ophthalmic solution 0.2% in both eyes 3 times per day. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Adverse Reactions:   Adverse events occurring in approximately 10-30% of the subjects, in descending order of incidence, included oral dryness, ocular hyperemia, burning and stinging, headache, blurring, foreign body sensation, fatigue/drowsiness, conjunctival follicles, ocular allergic reactions, and ocular pruritus. Pharmacokinetics:   After ocular administration of a 0.2% solution, plasma concentrations peaked within 1 to 4 hours and declined with a systemic half-life of approximately 3 hours. Treatment of an oral overdose includes supportive and symptomatic therapy; a patent airway should be maintained. Brimonidine tartrate ophthalmic solution 0.2% has not been studied in patients with hepatic or renal impairment; caution should be used in treating such patients. Carcinogenesis, mutagenesis, impairment of fertility:   No compound-related carcinogenic effects were observed in either mice or rats following a 21-month and 24-month study, respectively. This information does not assure that this product is safe, effective, or appropriate for you. Eight percent of subjects were discontinued from studies due to inadequately controlled intraocular pressure, which in 30% of these patients occurred during the first month of therapy. Repeat these steps for your other eye if so directed by your doctor. Do not stop using this medication without consulting your doctor. During pregnancy and moisture your personal circumstances and frequency can not be.. 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